CASA System

Comprehensive Computer Assisted Sperm Analysis

CASA System is a modular software solution designed to perform detailed analysis of sperm parameters. It offers a complete set of tools for motility, morphology and DNA fragmentation analysis with interactive features, batch processing and multi-sample acceptance for efficient and accurate results.

Powerful Analysis Modules

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Motility

Motility module performs motility analysis of the sperms in the input video. The motility analysis can be performed both on live sample as well as previously recorded sample.

Parameters Computed:

  • VCL, curvilinear velocity (µm/s)
  • VSL, straight-line velocity (µm/s)
  • VAP, average path velocity (µm/s)
  • ALH, amplitude of lateral head displacement (µm)
  • LIN, linearity
  • WOB, wobble
  • STR, straightness
  • BCF, beat-cross frequency (Hz)
  • MAD, mean angular displacement (degrees)
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Morphology

Morphology analysis module helps perform a parametric study of the spermatozoa and compute key morphology parameters.

Parameters Computed:

  • Area of the head
  • Perimeter of the head
  • Length and width of the head
  • Circularity of the sperm head
  • Elongation of the sperm head
  • The acrosome content in the sperm head

Defects Detected (as per WHO):

  • Head defect
  • Tail defect
  • Neck and Mid-piece defect
  • Cytoplasmic defect
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DNA Fragmentation

Sperm DNA Fragmentation test provides additional fertility potential of the semen based on Sperm Chromatin Dispersion principle and identifies different classes of spermatozoa.

Classes Identified:

  • Big Halo
  • Medium Halo
  • Small Halo
  • Without Halo
  • Degraded Halo

Based on the detection of different classes the DNA Fragmentation Index (DFI) is calculated representing the percentage of fragmented sperms.

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Batch Processing

Analyse multiple sperms at multiple fields in a single record analysis.

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Multiple Sample Acceptance

Accept and analyse multiple samples simultaneously for higher efficiency.

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Interactive Software

Interactive tools to record concentration of White blood cell, Immature germ cells and Round cells.

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Flexible Adjustment

Flexible adjustment tool to select sperms enabling work on both bright field and phase contrast.

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Comprehensive Reports

Software records results in Millions along with morphological parameters.

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